In the fast-paced world of corporate R&D, it’s difficult to find positions that allow for long-term development of difficult skills. Graduate school gave me a chance to reset, re-focus on computation and difficult experimental methods, and take the time to develop the laboratory and computational skills needed to contribute to science in 2026.
Electron tomography
Electron tomography allows one-of-a-kind samples to be studied in 3D at very high resolution. In my PhD, I studied polyamide membranes for reverse osmosis using high angle annular darkfield scanning transmission electron microscopy (HAADF-STEM). When an hyperspectral electron energy loss spectroscopy (EELS) image is acquired in the exact same area as the tomography tilt series, it becomes possible to estimate the three-dimensional density distribution of the sample.
Single particle analysis
Single particle analysis (SPA) is a method, originally developed for structural biology, that computes 3D reconstructions from large numbers of randomly-oriented, structurally-similar particles. In materials science, electron microscopy is typically used to study defects, interfaces, or other sui generis structures, and so structural similarity typically cannot be assumed. By studying a highly stable class of octahedral rhenium chalcogenide clusters, I was able to demonstrate that SPA can be applied to the inorganic sciences at true atomic resolution.
Electron microscopy simulation
Many scientific experiments seek to push the limits of what can be measured. If a signal was easy to measure, it probably would have been measured long ago, by someone else. At this limit simulation becomes essential to validate the correctness of results and understand the limits what can be learned from a proposed experiment.
Electron energy loss spectroscopy
Electron energy loss spectroscopy (EELS) is a microanalytical technique that can measure chemical properties of materials at high sensitivity and high resolution. Equipped with an experimental EELS detector, our group researched new methods of processing EELS data to improve the microstructural understanding of separation membranes.